2009-01-01 · Review A Framework for Assessing Inter-individual Variability in Pharmacokinetics Using Virtual Human Populations and Integrating General Knowledge of Physical Chemistry, Biology, Anatomy, Physiology and Genetics: A Tale of â€˜Bottom-Upâ€™ vs â€˜Top-Downâ€™ Recognition of CovariatesMasoud Jamei, 1 Gemma L Dickinson, 2 Amin Rostami-Hodjegan, 1 3 * [email protected] 1 Simcyp

Amin Rostami-Hodjegan, Professor of Systems Pharmacology, University of Manchester Amin is a Professor of Systems Pharmacology at the Centre for Applied Pharmacokinetic Research (CAPKR) in the School of Pharmacy and Pharmaceutical Sciences at the University of Manchester. He has an active program of training PhD students in

University of Manchester, UK; email: kevin.feng@Certara.com USP 1 USP 2 USP 3 USP 4 Figure 1. In Vitro dissolution profiles (n=3) of nifedipine IR capsule in FaSSGF. FaSSGFst=FaSSGF at pH 1.6 with water, FaSSGFoj=FaSSGF at pH 3.4 with grapefruit juice 2014, Pocket/Paperback. Köp boken Biosimulation in Biomedical Research, Health Care and Drug Development hos oss! Jill Barber, Matthew R. Russell, Amin Rostami-Hodjegan, Brahim Achour. Characterization of CYP2B6 K262R allelic variants by quantitative allele-specific proteomics using a QconCAT standard.

Simcyp Limited (a Certara Company), Sheffield, UK; 2. Manchester School of Pharmacy, University of Manchester, UK • Following a meal, physiological changes occur that can impact upon drug absorption and elimination. 16 Rostami-Hodjegan, A, Amin, AM, Spencer, EP, Lennard, MS, Tucker, GT, Flanagan, RJ. Influence of dose, cigarette smoking, age, sex, and metabolic activity on plasma clozapine concentrations: a predictive model and nomograms to aid clozapine dose adjustment and to assess compliance in individual patients. J Clin Psychopharmacol 2004; 24: 70 –8. Jiansong Yang, Masoud Jamei, Amir Heydari, Karen R. Yeo, Rafael de la Torre, Magí Farré, Geoffrey T. Tucker, and Amin Rostami-Hodjegan Journal of Psychopharmacology 2006 20 : 6 , 842-849 Download Citation Jiansong Yang, Masoud Jamei, Karen Rowland Yeo, Geoffrey T. Tucker and Amin Rostami-Hodjegan, “ Prediction of Intestinal First-Pass Drug Metabolism”, Current Drug Kairui Feng1, Robert H. Leary1, Michael Dunlavey1, Amin Rostami-Hodjegan1,2 1. Certara, USA; 2. University of Manchester, UK; email: kevin.feng@Certara.com USP 1 USP 2 USP 3 USP 4 Figure 1.

Rachel H. Rose1, Kevin Feng1, David B. Turner1, Amin Rostami-Hodjegan1,2, Masoud Jamei1 1. Simcyp Limited (a Certara Company), Sheffield, UK; 2. Manchester School of Pharmacy, University of Manchester, UK • Following a meal, physiological changes occur that can impact upon drug absorption and elimination.

Amin Rostami‐Hodjegan, PhD, PharmD, FCP, Stopford Building, Oxford Road, Manchester, United Kingdom of Great Britain and Northern Ireland, M13 9PT UK. Email: amin.rostami@manchester.ac.uk. Search for more papers by this author [1] Brahim Achour, Matthew R. Russel, Jill Barber, and Amin Rostami-Hodjegan, Simultaneous Quantification of the Abundance of Several Cytochrome P450 and Uridine 59-Diphospho-Glucuronosyltransferase Enzymes in Human Liver Microsomes Using Multiplexed Targeted Proteomics, Drug Metab Dispos 42:500–510 (2014) Title: Cytochrome P450 Turnover: Regulation of Synthesis and Degradation, Methods for Determining Rates, and Implications for the Prediction of Drug Interactions VOLUME: 9 ISSUE: 5 Author(s):Jiansong Yang, Mingxiang Liao, Magang Shou, Masoud Jamei, Karen Rowland Yeo, Geoffrey T. Tucker and Amin Rostami-Hodjegan Affiliation:Simcyp Limited, Blades Enterprise Centre, John Street, Sheffield S2 4SU CiteScore: 3.8 ℹ CiteScore: 2019: 3.8 CiteScore measures the average citations received per peer-reviewed document published in this title. CiteScore values are based on citation counts in a range of four years (e.g. 2016-2019) to peer-reviewed documents (articles, reviews, conference papers, data papers and book chapters) published in the same four calendar years, divided by the number of Amin Rostami-Hodjegan.

Christophe, Bevernage, Jan, Nguyen, Mai Anh, Lindley, David, Carr, Robert och Rostami-Hodjegan, Amin, IMI – Oral biopharmaceutics tools

Manchester School of Pharmacy, University of Manchester, UK • Following a meal, physiological changes occur that can impact upon drug absorption and elimination. Thomas M. Polasek, Carl M. J. Kirkpatrick, and Amin Rostami-Hodjegan. Therapeutic Advances in Drug Safety 2019 10.1177/2042098619894147 Download Citation. Amin Rostami-Hodjegan's 405 research works with 11,975 citations and 7,405 reads, including: Six years of progress in the oral biopharmaceutics area - A summary from the IMI OrBiTo project 16 Rostami-Hodjegan, A, Amin, AM, Spencer, EP, Lennard, MS, Tucker, GT, Flanagan, RJ. Influence of dose, cigarette smoking, age, sex, and metabolic activity on plasma clozapine concentrations: a predictive model and nomograms to aid clozapine dose adjustment and to assess compliance in individual patients.

Simcyp Limited (a Certara Company), Sheffield, UK; 2. Manchester School of Pharmacy, University of Manchester, UK • Following a meal, physiological changes occur that … Amin Rostami-Hodjegan, Professor of Systems Pharmacology, University of Manchester Amin is a Professor of Systems Pharmacology at the Centre for Applied Pharmacokinetic Research (CAPKR) in the School of Pharmacy and Pharmaceutical Sciences at the University of Manchester. He has an active program of training PhD students in Research Explorer. The University of Manchester's research has real-world impact beyond academia.
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Köp boken Biosimulation in Biomedical Research, Health Care and Drug Development hos oss!

University of Manchester, UK; email: kevin.feng@Certara.com USP 1 USP 2 USP 3 USP 4 Figure 1. In Vitro dissolution profiles (n=3) of nifedipine IR capsule in FaSSGF.
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FAST BREAKING PAPERS - 2008 April 2008 Amin Rostami-Hodjegan talks with ScienceWatch.com and answers a few questions about this month's Fast Breaking Paper in the field of Pharmacology & Toxicology. Article Title: Simulation and prediction of in vivo drug metabolism in human populations from in vitro data

PubMed PMID: 27506526. 11: Chen R, Rostami-Hodjegan A, Wang H, Berk D, Shi J, Hu P. Application of a physiologically based pharmacokinetic model for the evaluation of single-point plasma phenotyping method of CYP2D6. 2019-12-11 amin.rostami@manchester.ac.uk; Centre for Applied Pharmacokinetic Research (CAPKR), University of Manchester, UK, and Certara, Princeton, New Jersey, USA. Correspondence: Amin Rostami‐Hodjegan (amin.rostami@manchester.ac.uk)Search for more papers by this author Amin Rostami‐Hodjegan, PhD, PharmD, FCP, Stopford Building, Oxford Road, Manchester, United Kingdom of Great Britain and Northern Ireland, M13 9PT UK. Email: amin.rostami@manchester.ac.uk. Search for more papers by this author 2021-04-01 2007-02-01 Amin Rostami-Hodjegan is the author of ADME (0.0 avg rating, 0 ratings, 0 reviews, published 2009) and Biosimulation in Biomedical Research, Health Care In vivo enzyme levels are governed by the rates of de novo enzyme synthesis and degradation.

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Sandra Suarez-Sharp, Anders Lindahl, Tycho Heimbach, Amin Rostami-Hodjegan, Michael B Bolger, Siladitya Ray Chaudhuri and Bart Hens. Övriga författare.

Article Title: Simulation and prediction of in vivo drug metabolism in human populations from in vitro data Rachel H. Rose1, Kevin Feng1, David B. Turner1, Amin Rostami-Hodjegan1,2, Masoud Jamei1 1. Simcyp Limited (a Certara Company), Sheffield, UK; 2. Manchester School of Pharmacy, University of Manchester, UK • Following a meal, physiological changes occur that can impact upon drug absorption and elimination. 16 Rostami-Hodjegan, A, Amin, AM, Spencer, EP, Lennard, MS, Tucker, GT, Flanagan, RJ. Influence of dose, cigarette smoking, age, sex, and metabolic activity on plasma clozapine concentrations: a predictive model and nomograms to aid clozapine dose adjustment and to assess compliance in individual patients. J Clin Psychopharmacol 2004; 24: 70 –8.